sgp130fc (R&D Systems)
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sgp130fc
Sgp130fc, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 7 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sgp130fc/Recombinant+Rat+gp130+Fc+Chimera+Protein%2C+CF/pm41962618-55-8-9
Average 94 stars, based on 7 article reviews
Sgp130fc, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 7 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sgp130fc/Recombinant+Rat+gp130+Fc+Chimera+Protein%2C+CF/pm41962618-55-8-9
Average 94 stars, based on 7 article reviews
sgp130fc - by Bioz Stars,
2026-09
94/100 stars
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Recombinant:Article Title: Sgp130Fc regulates IL-6/JAK2/STAT3 trans-signaling pathway in rat vocal fold fibroblast activation. Article Snippet: Acute vocal fold injury activates rat vocal fold fibroblasts (VFFs) and upregulates IL-6 expression.. We investigated whether soluble gp130Fc (sgp130Fc) modulates IL-6 trans-signaling via the JAK2/STAT3 pathway.. We established a vocal fold injury model, isolated primary VFFs, and silenced JAK2 expression using siRNA. Article Title: IL-6 dysregulation originates in dendritic cells and mediates graft-versus-host disease via classical signaling. Article Snippet: For IL-6R blockade studies, rat anti-mouse IL-6R monoclonal antibody (MR16-1; Chugai Pharmaceutical Co.) was administered intraperitoneally at 500mg per dose on day 1 and days 13 and 17 posttransplantation as described.22 Rat immunoglobulin G was used as an isotype control (Sigma-Aldrich). .. Serum soluble receptor and cytokines Soluble receptor levels were assessed by commercial enzymelinked immunosorbent assay kits (R&D Systems): murine sIL-6R (Mouse IL-6R a DuoSet ELISA), sgp130 (Mouse gp130 DuoSet ELISA), and Article Title: Nonspecific Inhibition of IL6 Family Cytokine Signalling by Soluble gp130 Article Snippet: .. Recombinant human (rh)CNTF (257-NT, R&D Systems, Minneapolis, MN, USA), rhCT1 (612-CD, R&D Systems, Minneapolis, MN, USA), rhIL6 (206-IL, R&D Systems, Minneapolis, MN, USA), rhIL11 (Z03108, Genscript, Minneapolis, MN, USA), rhLIF (7734-LF, R&D Systems, Minneapolis, MN, USA), rhOSM (PHC5015, ThermoFisher Scientific, San Francisco, CA, USA), Transduction:Article Title: Sgp130Fc regulates IL-6/JAK2/STAT3 trans-signaling pathway in rat vocal fold fibroblast activation. Article Snippet: Acute vocal fold injury activates rat vocal fold fibroblasts (VFFs) and upregulates IL-6 expression.. We investigated whether soluble gp130Fc (sgp130Fc) modulates IL-6 trans-signaling via the JAK2/STAT3 pathway.. We established a vocal fold injury model, isolated primary VFFs, and silenced JAK2 expression using siRNA. Enzyme-linked Immunosorbent Assay:Article Title: IL-6 dysregulation originates in dendritic cells and mediates graft-versus-host disease via classical signaling. Article Snippet: For IL-6R blockade studies, rat anti-mouse IL-6R monoclonal antibody (MR16-1; Chugai Pharmaceutical Co.) was administered intraperitoneally at 500mg per dose on day 1 and days 13 and 17 posttransplantation as described.22 Rat immunoglobulin G was used as an isotype control (Sigma-Aldrich). .. Serum soluble receptor and cytokines Soluble receptor levels were assessed by commercial enzymelinked immunosorbent assay kits (R&D Systems): murine sIL-6R (Mouse IL-6R a DuoSet ELISA), sgp130 (Mouse gp130 DuoSet ELISA), and Injection:Article Title: Interleukin-6 trans-signaling inhibition prevents oxidative stress in a mouse model of early diabetic retinopathy Article Snippet: .. After eight weeks of hyperglycemia, appropriate treatment groups received 5 mg/kg Article Title: Diabetes Induced Alterations in Murine Vitreous Proteome Are Mitigated by IL-6 Trans-Signaling Inhibition Article Snippet: .. Treated mice received 5 mg/kg Binding Assay:Article Title: Interleukin-6 Downregulates the Expression of Vascular Endothelial-Cadherin and Increases Permeability in Renal Glomerular Endothelial Cells via the Trans-Signaling Pathway. Article Snippet: .. Additionally, Article Title: Interleukin-6 Downregulates the Expression of Vascular Endothelial-Cadherin and Increases Permeability in Renal Glomerular Endothelial Cells via the Trans-Signaling Pathway Article Snippet: .. Additionally, Inhibition:Article Title: Blockade of interleukin-6 trans-signaling prevents mitochondrial dysfunction and cellular senescence in retinal endothelial cells. Article Snippet: IL-6 trans-signaling (IL-6 TS) was activated with IL-6 (50 ng/mL) and sIL-6R (150 ng/mL; PeproTech, Rocky Hill, NJ, USA) or with Hyper IL-6 (50 ng/mL; kindly provided by Dr. Stefan Rose-John) overnight. .. For inhibition of IL-6 TS, cells were pretreated with Activation Assay:Article Title: Blockade of interleukin-6 trans-signaling prevents mitochondrial dysfunction and cellular senescence in retinal endothelial cells. Article Snippet: IL-6 trans-signaling (IL-6 TS) was activated with IL-6 (50 ng/mL) and sIL-6R (150 ng/mL; PeproTech, Rocky Hill, NJ, USA) or with Hyper IL-6 (50 ng/mL; kindly provided by Dr. Stefan Rose-John) overnight. .. For inhibition of IL-6 TS, cells were pretreated with |
